May 1, 2024

Leqvio Side Effects: A Comprehensive Analysis for Informed Use

Understanding Leqvio: A Comprehensive Look at Side Effects, Uses, and Precautions

Leqvio (Inclisiran) is a prescription medication primarily used to reduce low-density lipoprotein cholesterol (LDL-C), commonly referred to as 'bad cholesterol', in adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease.

An Overview of Common and Serious Side Effects Associated with Leqvio

Like any medication, Leqvio is associated with certain common and severe side effects. It's crucial to be aware of these potential reactions and to discuss them with your healthcare provider before starting treatment.

Common Side Effects

While most side effects do not require immediate medical attention, they can cause discomfort or concern. These include muscle pain, joint pain, and bladder pain, as well as injection site reactions like redness, pain, or bruising. Other side effects encompass urinary tract infections, diarrhea, and bronchitis.

Serious Side Effects

Serious side effects manifest rarely, but when they do occur, they require immediate medical attention. One severe side effect is trouble breathing; other potentially grave reactions include serious allergic reactions that may cause hives, itching, swelling, dizziness, and trouble breathing.

Medical Considerations and Precautions

Several factors influence a patient's potential response to Leqvio. Patients with severe liver problems, for instance, or those susceptible to allergies may not be ideal candidates for this medication. Another essential element to consider is potential alcohol interaction, so discussing current alcohol consumption levels with your healthcare provider is vital. Safety during pregnancy and breastfeeding is still uncertain, necessitating consultation with a healthcare provider.

Leqvio Use for Specific Conditions like Familial Hypercholesterolemia

Leqvio has shown particular efficacy in treating patients with heterozygous familial hypercholesterolemia (HeFH), who require additional lowering of their LDL cholesterol. The medication is administered as an injection under the skin at a healthcare facility, with most receiving it well. Regular check-ups and blood tests are essential to monitor its effectiveness and detect any adverse effects.

Reporting of Side Effects

It is important to record any side effects experienced and inform your healthcare provider immediately upon noticing any severe side effects. In the US, patients can also report these to the FDA at 1-800-FDA-1088 or via In Canada, side effects can be reported to Health Canada at 1-866-234-2345.

Emphasizing the Importance of Patient Awareness

All patients should remain informed about the potential side effects of their medications. This awareness helps report any adverse effects to healthcare authorities promptly, where further monitoring and analysis can be carried out.

Medication Affordability through LEQVIO Co-pay Program

The LEQVIO Co-pay Program aims to be a financial relief resource for individuals with commercial or Medicare and supplemental insurance. Qualifying individuals may be eligible to pay as little as $0 for their medication.


Leqvio has made significant strides in LDL-C reduction in patients requiring greater control of their cholesterol levels. Side effects, while notable, are not uncommon and generally well-tolerated. The drug's impact on LDL cholesterol management continues to offer potential benefits for cardiovascular disease treatment. Note: This article is not intended as medical advice; always consult your healthcare provider or pharmacist to discuss potential side effects, or if symptoms persist or worsen.

Leave a Reply

Your email address will not be published. Required fields are marked *


Welcome to the blog all about your mental, physical and last but not least, your spiritual health, and well-being.
linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram